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Legend
UniProt: | Protein identifier in UniProt database. It is also reported as SWISSPROT_ID. |
PDB: | Protein Data Bank code of the wild-type protein. It is also reported as PDB_wild. |
Chain: | Protein chain in the PDB file. It is also reported ad MUTATED_CHAIN. |
Mutation: | Mutation with format XPOSY (X/Y: wild-type/mutant residue, POS: PDB or Sequence position). |
T: | Temperature (°C). |
pH: | The pH value of the experiment. |
State: | Number of transition states. |
ΔGH2O: | Unfolding free energy at zero denaturant concentration (kcal/mol). |
ΔΔGH2O: | ΔGH2O(mutant) - ΔGH2O(wild-type). |
ΔGu: | Unfolding free energy in presence of denaturant(kcal/mol). |
ΔΔGu: | ΔGu(mutant) - ΔGu(wild-type).
or obtained by Schellman equation. |
Tm: | Midpoint temperature for thermal denaturation methods [°C]. |
ΔTm: | Tm(mutant) - Tm(wild) [°C]. |