I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
           313    S    V   -0.61   7.0   25
           313    S    L   -1.20   7.0   25
           313    S    I   -0.33   7.0   25
           313    S    M   -0.49   7.0   25
           313    S    F   -0.63   7.0   25
           313    S    W   -0.90   7.0   25
           313    S    Y   -0.89   7.0   25
           313    S    G   -1.20   7.0   25
           313    S    A   -1.00   7.0   25
           313    S    P   -1.49   7.0   25
           313    S    T   -0.93   7.0   25
           313    S    C   -1.90   7.0   25
           313    S    H   -0.75   7.0   25
           313    S    R   -1.25   7.0   25
           313    S    K   -0.37   7.0   25
           313    S    Q   -1.00   7.0   25
           313    S    E   -0.58   7.0   25
           313    S    N   -0.97   7.0   25
           313    S    D   -0.12   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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