I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
           330    L    V   -0.85   7.0   25
           330    L    I   -1.09   7.0   25
           330    L    M   -1.20   7.0   25
           330    L    F   -0.63   7.0   25
           330    L    W   -0.63   7.0   25
           330    L    Y   -1.06   7.0   25
           330    L    G   -3.74   7.0   25
           330    L    A   -3.77   7.0   25
           330    L    P   -1.75   7.0   25
           330    L    S   -3.33   7.0   25
           330    L    T   -3.28   7.0   25
           330    L    C   -3.23   7.0   25
           330    L    H   -1.66   7.0   25
           330    L    R   -2.18   7.0   25
           330    L    K   -2.30   7.0   25
           330    L    Q   -2.03   7.0   25
           330    L    E   -1.36   7.0   25
           330    L    N   -2.73   7.0   25
           330    L    D   -3.59   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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