I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
           333    Q    V    1.24   7.0   25
           333    Q    L    0.66   7.0   25
           333    Q    I    0.88   7.0   25
           333    Q    M   -0.84   7.0   25
           333    Q    F    0.43   7.0   25
           333    Q    W    0.33   7.0   25
           333    Q    Y    0.16   7.0   25
           333    Q    G   -0.63   7.0   25
           333    Q    A   -0.27   7.0   25
           333    Q    P   -0.49   7.0   25
           333    Q    S   -0.91   7.0   25
           333    Q    T   -0.32   7.0   25
           333    Q    C    0.37   7.0   25
           333    Q    H   -0.54   7.0   25
           333    Q    R   -0.74   7.0   25
           333    Q    K    0.19   7.0   25
           333    Q    E    0.83   7.0   25
           333    Q    N   -1.65   7.0   25
           333    Q    D   -0.11   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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