I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
           342    S    V    1.76   7.0   25
           342    S    L    1.96   7.0   25
           342    S    I    1.65   7.0   25
           342    S    M    1.22   7.0   25
           342    S    F    0.97   7.0   25
           342    S    W    1.36   7.0   25
           342    S    Y    0.65   7.0   25
           342    S    G   -0.38   7.0   25
           342    S    A    1.02   7.0   25
           342    S    P    0.72   7.0   25
           342    S    T    1.03   7.0   25
           342    S    C    0.73   7.0   25
           342    S    H    1.32   7.0   25
           342    S    R    0.29   7.0   25
           342    S    K    0.78   7.0   25
           342    S    Q    0.97   7.0   25
           342    S    E    1.22   7.0   25
           342    S    N    1.23   7.0   25
           342    S    D    1.16   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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