I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
           102    R    V   -0.07   7.0   25
           102    R    L    0.67   7.0   25
           102    R    I    0.27   7.0   25
           102    R    M    0.13   7.0   25
           102    R    F    0.31   7.0   25
           102    R    W    0.02   7.0   25
           102    R    Y    0.47   7.0   25
           102    R    G    0.03   7.0   25
           102    R    A   -0.08   7.0   25
           102    R    P   -0.23   7.0   25
           102    R    S   -0.25   7.0   25
           102    R    T   -0.24   7.0   25
           102    R    C    0.44   7.0   25
           102    R    H   -0.38   7.0   25
           102    R    K   -0.04   7.0   25
           102    R    Q   -0.04   7.0   25
           102    R    E   -0.15   7.0   25
           102    R    N   -0.12   7.0   25
           102    R    D   -0.75   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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