I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
            36    G    V   -0.11   5.0   60
            36    G    L   -0.27   5.0   60
            36    G    I    0.05   5.0   60
            36    G    M   -0.99   5.0   60
            36    G    F   -1.76   5.0   60
            36    G    W   -1.26   5.0   60
            36    G    Y   -1.59   5.0   60
            36    G    A   -0.49   5.0   60
            36    G    P   -0.35   5.0   60
            36    G    S   -1.39   5.0   60
            36    G    T   -1.79   5.0   60
            36    G    C   -1.02   5.0   60
            36    G    H   -1.43   5.0   60
            36    G    R   -1.87   5.0   60
            36    G    K   -1.55   5.0   60
            36    G    Q   -0.59   5.0   60
            36    G    E    0.27   5.0   60
            36    G    N   -1.18   5.0   60
            36    G    D   -1.34   5.0   60


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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