I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
            35    F    V   -1.88   7.0   25
            35    F    L   -0.43   7.0   25
            35    F    I   -0.89   7.0   25
            35    F    M   -1.02   7.0   25
            35    F    W   -0.22   7.0   25
            35    F    Y   -0.38   7.0   25
            35    F    G   -3.35   7.0   25
            35    F    A   -2.49   7.0   25
            35    F    P   -1.51   7.0   25
            35    F    S   -1.79   7.0   25
            35    F    T   -1.54   7.0   25
            35    F    C   -1.04   7.0   25
            35    F    H   -1.80   7.0   25
            35    F    R   -1.31   7.0   25
            35    F    K   -1.63   7.0   25
            35    F    Q   -1.64   7.0   25
            35    F    E   -1.06   7.0   25
            35    F    N   -1.49   7.0   25
            35    F    D   -1.67   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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