I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW     DDG    pH    T
             6    F    V   -2.38   7.0   25
             6    F    L   -2.31   7.0   25
             6    F    I   -0.99   7.0   25
             6    F    M   -1.44   7.0   25
             6    F    W   -0.93   7.0   25
             6    F    Y   -1.51   7.0   25
             6    F    G   -4.33   7.0   25
             6    F    A   -2.63   7.0   25
             6    F    P   -2.33   7.0   25
             6    F    S   -2.45   7.0   25
             6    F    T   -1.91   7.0   25
             6    F    C   -2.41   7.0   25
             6    F    H   -3.16   7.0   25
             6    F    R   -2.17   7.0   25
             6    F    K   -2.23   7.0   25
             6    F    Q   -2.28   7.0   25
             6    F    E   -1.72   7.0   25
             6    F    N   -2.71   7.0   25
             6    F    D   -2.39   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
             DDG<0: Decrease Stability
             DDG>0: Increase Stability
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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