I-Mutant2.0

Last Update 27/12/06



        
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**                                                                       **
**                             I-Mutant v2.0                             **
**         Predictor of Protein Stability Changes upon Mutations         **
**                                                                       **
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      SEQ File: fileseq.txt

      Position   WT  NEW   Stability  RI    pH    T
           504    Q    V    Decrease   0   7.0   25
           504    Q    L    Increase   5   7.0   25
           504    Q    I    Increase   1   7.0   25
           504    Q    M    Decrease   3   7.0   25
           504    Q    F    Increase   2   7.0   25
           504    Q    W    Decrease   1   7.0   25
           504    Q    Y    Increase   2   7.0   25
           504    Q    G    Decrease   6   7.0   25
           504    Q    A    Decrease   4   7.0   25
           504    Q    P    Decrease   2   7.0   25
           504    Q    S    Decrease   6   7.0   25
           504    Q    T    Decrease   5   7.0   25
           504    Q    C    Increase   3   7.0   25
           504    Q    H    Decrease   6   7.0   25
           504    Q    R    Decrease   3   7.0   25
           504    Q    K    Increase   1   7.0   25
           504    Q    E    Increase   4   7.0   25
           504    Q    N    Decrease   4   7.0   25
           504    Q    D    Decrease   1   7.0   25


      WT:  Aminoacid in Wild-Type Protein
      NEW: New Aminoacid after Mutation
      RI:  Reliability Index
      T:   Temperature in Celsius degrees
      pH:  -log[H+]



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*                                                                         *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting  *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310.                                         *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
*                                                                         *
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