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** **
** I-Mutant v2.0 **
** Predictor of Protein Stability Changes upon Mutations **
** **
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PDB File: pdb7sh6.ent Chain: _
Position WT NEW DDG pH T RSA
146 Y V 0.10 8.0 50 59.9
146 Y L 0.20 8.0 50 59.9
146 Y I -0.14 8.0 50 59.9
146 Y M -0.55 8.0 50 59.9
146 Y F -0.43 8.0 50 59.9
146 Y W -0.34 8.0 50 59.9
146 Y G -3.30 8.0 50 59.9
146 Y A -1.42 8.0 50 59.9
146 Y P -1.39 8.0 50 59.9
146 Y S -0.77 8.0 50 59.9
146 Y T -0.57 8.0 50 59.9
146 Y C 0.24 8.0 50 59.9
146 Y H -0.04 8.0 50 59.9
146 Y R -0.74 8.0 50 59.9
146 Y K -0.40 8.0 50 59.9
146 Y Q -0.36 8.0 50 59.9
146 Y E -0.03 8.0 50 59.9
146 Y N -0.96 8.0 50 59.9
146 Y D 0.75 8.0 50 59.9
WT: Aminoacid in Wild-Type Protein
NEW: New Aminoacid after Mutation
DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
DDG<0: Decrease Stability
DDG>0: Increase Stability
T: Temperature in Celsius degrees
pH: -log[H+]
RSA: Relative Solvent Accessible Area
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* *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310. *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
* *
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