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** **
** I-Mutant v2.0 **
** Predictor of Protein Stability Changes upon Mutations **
** **
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PDB File: pdb7sh6.ent Chain: _
Position WT NEW DDG pH T RSA
257 W V -1.85 8.0 50 0.0
257 W L -0.84 8.0 50 0.0
257 W I -1.72 8.0 50 0.0
257 W M -1.59 8.0 50 0.0
257 W F -2.25 8.0 50 0.0
257 W Y -2.25 8.0 50 0.0
257 W G -3.97 8.0 50 0.0
257 W A -2.88 8.0 50 0.0
257 W P -3.00 8.0 50 0.0
257 W S -2.97 8.0 50 0.0
257 W T -2.58 8.0 50 0.0
257 W C -2.18 8.0 50 0.0
257 W H -2.99 8.0 50 0.0
257 W R -3.02 8.0 50 0.0
257 W K -3.46 8.0 50 0.0
257 W Q -2.68 8.0 50 0.0
257 W E -2.89 8.0 50 0.0
257 W N -2.94 8.0 50 0.0
257 W D -3.54 8.0 50 0.0
WT: Aminoacid in Wild-Type Protein
NEW: New Aminoacid after Mutation
DDG: DG(NewProtein)-DG(WildType) in Kcal/mol
DDG<0: Decrease Stability
DDG>0: Increase Stability
T: Temperature in Celsius degrees
pH: -log[H+]
RSA: Relative Solvent Accessible Area
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* *
* Capriotti E, Fariselli P and Casadio R (2005). I-Mutant2.0: predicting *
* stability changes upon mutation from the protein sequence or structure. *
* Nucl. Acids Res. 33: W306-W310. *
* http://gpcr.biocomp.unibo.it/cgi/predictors/I-Mutant2.0/I-Mutant2.0.cgi *
* *
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