[
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 25.0,
      "pH": 7.5,
      "BUFFER_NAME": "HEPES",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "ln(kf)_H2O": 6.3,
      "ln(ku)_H2O": -1.72,
      "dGKIN_H2O": 19.87,
      "mf": -7.03,
      "mu": 1.38,
      "AUTHOR_KIN": "Maxwell, K.L., Wildes, D., Zarrine-Afsar, A., De Los Rios, M.A., Brown, A.G., Friel, C.T., Hedberg, L., Horng, J.-C., Bona, D., Miller, E.J., Vall\u00e9e-B\u00e9lisle, A., Main, E.R.G., Bemporad, F., Qiu, L., Teilum, K., Vu, N.-D., Edwards, A.M., Ruczinski, I., Poulsen, F.M., Kragelund, B.B., Michnick, S.W., Chiti, F., Bai, Y., Hagen, S.J., Serrano, L., Oliveberg, M., Raleigh, D.P., Wittung-Stafshede, P., Radford, S.E., Jackson, S.E., Sosnick, T.R., Marqusee, S., Davidson, A.R., Plaxco, K.W.",
      "REFERENCE_KIN": "Protein folding: defining a \u201cstandard\u201d set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci. 14, 602\u2013616. https://doi.org/10.1110/ps.041205428",
      "YEAR_KIN": 2005.0,
      "PMID_KIN": "15689503",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 25.0,
      "pH": 7.5,
      "BUFFER_NAME": "HEPES",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "ln(kf)_H2O": 6.3,
      "ln(ku)_H2O": -1.72,
      "dGKIN_H2O": 19.87,
      "mf": -7.03,
      "mu": 1.38,
      "AUTHOR_KIN": "Maxwell, K.L., Wildes, D., Zarrine-Afsar, A., De Los Rios, M.A., Brown, A.G., Friel, C.T., Hedberg, L., Horng, J.-C., Bona, D., Miller, E.J., Vall\u00e9e-B\u00e9lisle, A., Main, E.R.G., Bemporad, F., Qiu, L., Teilum, K., Vu, N.-D., Edwards, A.M., Ruczinski, I., Poulsen, F.M., Kragelund, B.B., Michnick, S.W., Chiti, F., Bai, Y., Hagen, S.J., Serrano, L., Oliveberg, M., Raleigh, D.P., Wittung-Stafshede, P., Radford, S.E., Jackson, S.E., Sosnick, T.R., Marqusee, S., Davidson, A.R., Plaxco, K.W.",
      "REFERENCE_KIN": "Protein folding: defining a \u201cstandard\u201d set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci. 14, 602\u2013616. https://doi.org/10.1110/ps.041205428",
      "YEAR_KIN": 2005.0,
      "PMID_KIN": "15689503",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.12,
      "mu": 1.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77971",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.12,
      "mu": 1.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77971",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y229L",
      "MUTATION_PDB": "Y3L",
      "SEC_STR": "Beta",
      "RSA": "5.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.23,
      "mu": 1.38,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77972",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y229L",
      "MUTATION_PDB": "Y3L",
      "SEC_STR": "Beta",
      "RSA": "5.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.23,
      "mu": 1.38,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77972",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "I232A",
      "MUTATION_PDB": "I6A",
      "SEC_STR": "Beta",
      "RSA": "37.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.85,
      "mu": 1.38,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77973",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "I232A",
      "MUTATION_PDB": "I6A",
      "SEC_STR": "Beta",
      "RSA": "37.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.85,
      "mu": 1.38,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77973",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "L233A",
      "MUTATION_PDB": "L7A",
      "SEC_STR": "Beta",
      "RSA": "4.3",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.62,
      "mu": 1.59,
      "PhiF_H2O": 0.32,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77974",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "L233A",
      "MUTATION_PDB": "L7A",
      "SEC_STR": "Beta",
      "RSA": "4.3",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.62,
      "mu": 1.59,
      "PhiF_H2O": 0.32,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77974",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T237A",
      "MUTATION_PDB": "T11A",
      "SEC_STR": "Coil",
      "RSA": "90.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.26,
      "mu": 2.18,
      "PhiF_H2O": 0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77975",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T237A",
      "MUTATION_PDB": "T11A",
      "SEC_STR": "Coil",
      "RSA": "90.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.26,
      "mu": 2.18,
      "PhiF_H2O": 0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77975",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "E241A",
      "MUTATION_PDB": "E15A",
      "SEC_STR": "Beta",
      "RSA": "60.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.55,
      "mu": 1.92,
      "PhiF_H2O": -0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77976",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "E241A",
      "MUTATION_PDB": "E15A",
      "SEC_STR": "Beta",
      "RSA": "60.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.55,
      "mu": 1.92,
      "PhiF_H2O": -0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77976",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T242A",
      "MUTATION_PDB": "T16A",
      "SEC_STR": "Beta",
      "RSA": "33.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.51,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77977",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T242A",
      "MUTATION_PDB": "T16A",
      "SEC_STR": "Beta",
      "RSA": "33.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.51,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77977",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T244A",
      "MUTATION_PDB": "T18A",
      "SEC_STR": "Beta",
      "RSA": "26.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.22,
      "mu": 1.63,
      "PhiF_H2O": -0.45,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77978",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T244A",
      "MUTATION_PDB": "T18A",
      "SEC_STR": "Beta",
      "RSA": "26.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.22,
      "mu": 1.63,
      "PhiF_H2O": -0.45,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77978",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A246G",
      "MUTATION_PDB": "A20G",
      "SEC_STR": "Coil",
      "RSA": "13.2",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.84,
      "mu": 2.01,
      "PhiF_H2O": 0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77979",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A246G",
      "MUTATION_PDB": "A20G",
      "SEC_STR": "Coil",
      "RSA": "13.2",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.84,
      "mu": 2.01,
      "PhiF_H2O": 0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77979",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D248A",
      "MUTATION_PDB": "D22A",
      "SEC_STR": "Coil",
      "RSA": "42.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 2.05,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77980",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D248A",
      "MUTATION_PDB": "D22A",
      "SEC_STR": "Coil",
      "RSA": "42.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 2.05,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77980",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T251A",
      "MUTATION_PDB": "T25A",
      "SEC_STR": "Helix",
      "RSA": "30.3",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 1.55,
      "PhiF_H2O": -0.81,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77981",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T251A",
      "MUTATION_PDB": "T25A",
      "SEC_STR": "Helix",
      "RSA": "30.3",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 1.55,
      "PhiF_H2O": -0.81,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77981",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A252G",
      "MUTATION_PDB": "A26G",
      "SEC_STR": "Helix",
      "RSA": "0.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -10.3,
      "mu": 1.34,
      "PhiF_H2O": 0.31,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77982",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A252G",
      "MUTATION_PDB": "A26G",
      "SEC_STR": "Helix",
      "RSA": "0.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -10.3,
      "mu": 1.34,
      "PhiF_H2O": 0.31,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77982",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "K254G",
      "MUTATION_PDB": "K28G",
      "SEC_STR": "Helix",
      "RSA": "59.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.22,
      "mu": 1.88,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77983",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "K254G",
      "MUTATION_PDB": "K28G",
      "SEC_STR": "Helix",
      "RSA": "59.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.22,
      "mu": 1.88,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77983",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V255A",
      "MUTATION_PDB": "V29A",
      "SEC_STR": "Helix",
      "RSA": "50.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.69,
      "mu": 1.84,
      "PhiF_H2O": 0.26,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77984",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V255A",
      "MUTATION_PDB": "V29A",
      "SEC_STR": "Helix",
      "RSA": "50.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.69,
      "mu": 1.84,
      "PhiF_H2O": 0.26,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77984",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "F256L",
      "MUTATION_PDB": "F30L",
      "SEC_STR": "Helix",
      "RSA": "2.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 1.8,
      "PhiF_H2O": 0.05,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77985",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "F256L",
      "MUTATION_PDB": "F30L",
      "SEC_STR": "Helix",
      "RSA": "2.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.74,
      "mu": 1.8,
      "PhiF_H2O": 0.05,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77985",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "K257G",
      "MUTATION_PDB": "K31G",
      "SEC_STR": "Helix",
      "RSA": "41.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.55,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77986",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "K257G",
      "MUTATION_PDB": "K31G",
      "SEC_STR": "Helix",
      "RSA": "41.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.55,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77986",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Q258G",
      "MUTATION_PDB": "Q32G",
      "SEC_STR": "Helix",
      "RSA": "66.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.69,
      "mu": 1.59,
      "PhiF_H2O": 0.55,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77987",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Q258G",
      "MUTATION_PDB": "Q32G",
      "SEC_STR": "Helix",
      "RSA": "66.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.69,
      "mu": 1.59,
      "PhiF_H2O": 0.55,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77987",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y259A",
      "MUTATION_PDB": "Y33A",
      "SEC_STR": "Helix",
      "RSA": "34.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.21,
      "mu": 2.26,
      "PhiF_H2O": 0.2,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77988",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y259A",
      "MUTATION_PDB": "Y33A",
      "SEC_STR": "Helix",
      "RSA": "34.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.21,
      "mu": 2.26,
      "PhiF_H2O": 0.2,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77988",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A260G",
      "MUTATION_PDB": "A34G",
      "SEC_STR": "Helix",
      "RSA": "1.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.46,
      "mu": 1.76,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77989",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "A260G",
      "MUTATION_PDB": "A34G",
      "SEC_STR": "Helix",
      "RSA": "1.9",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.46,
      "mu": 1.76,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77989",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "N261G",
      "MUTATION_PDB": "N35G",
      "SEC_STR": "Helix",
      "RSA": "77.1",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.41,
      "mu": 1.67,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77990",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "N261G",
      "MUTATION_PDB": "N35G",
      "SEC_STR": "Helix",
      "RSA": "77.1",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.41,
      "mu": 1.67,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77990",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "N263A",
      "MUTATION_PDB": "N37A",
      "SEC_STR": "Coil",
      "RSA": "54.1",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.55,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77991",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "N263A",
      "MUTATION_PDB": "N37A",
      "SEC_STR": "Coil",
      "RSA": "54.1",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.98,
      "mu": 1.55,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77991",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V265A",
      "MUTATION_PDB": "V39A",
      "SEC_STR": "Coil",
      "RSA": "7.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.03,
      "mu": 1.42,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77992",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V265A",
      "MUTATION_PDB": "V39A",
      "SEC_STR": "Coil",
      "RSA": "7.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.03,
      "mu": 1.42,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77992",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "G267A",
      "MUTATION_PDB": "G41A",
      "SEC_STR": "Coil",
      "RSA": "22.6",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.23,
      "mu": 1.84,
      "PhiF_H2O": -0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77993",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "G267A",
      "MUTATION_PDB": "G41A",
      "SEC_STR": "Coil",
      "RSA": "22.6",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.23,
      "mu": 1.84,
      "PhiF_H2O": -0.02,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77993",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y271L",
      "MUTATION_PDB": "Y45L",
      "SEC_STR": "Beta",
      "RSA": "36.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.89,
      "mu": 2.22,
      "PhiF_H2O": 0.3,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77994",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "Y271L",
      "MUTATION_PDB": "Y45L",
      "SEC_STR": "Beta",
      "RSA": "36.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.89,
      "mu": 2.22,
      "PhiF_H2O": 0.3,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77994",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D272A",
      "MUTATION_PDB": "D46A",
      "SEC_STR": "Beta",
      "RSA": "49.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.88,
      "mu": 1.46,
      "PhiF_H2O": 0.96,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77995",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D272A",
      "MUTATION_PDB": "D46A",
      "SEC_STR": "Beta",
      "RSA": "49.7",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.88,
      "mu": 1.46,
      "PhiF_H2O": 0.96,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77995",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D273A",
      "MUTATION_PDB": "D47A",
      "SEC_STR": "Coil",
      "RSA": "55.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.26,
      "mu": 1.26,
      "PhiF_H2O": 0.67,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77996",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "D273A",
      "MUTATION_PDB": "D47A",
      "SEC_STR": "Coil",
      "RSA": "55.8",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -6.26,
      "mu": 1.26,
      "PhiF_H2O": 0.67,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77996",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T275A",
      "MUTATION_PDB": "T49A",
      "SEC_STR": "Coil",
      "RSA": "58.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.32,
      "mu": 1.59,
      "PhiF_H2O": 0.84,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77997",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T275A",
      "MUTATION_PDB": "T49A",
      "SEC_STR": "Coil",
      "RSA": "58.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.32,
      "mu": 1.59,
      "PhiF_H2O": 0.84,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77997",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T277A",
      "MUTATION_PDB": "T51A",
      "SEC_STR": "Beta",
      "RSA": "15.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.99,
      "mu": 1.55,
      "PhiF_H2O": 0.44,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77998",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T277A",
      "MUTATION_PDB": "T51A",
      "SEC_STR": "Beta",
      "RSA": "15.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.99,
      "mu": 1.55,
      "PhiF_H2O": 0.44,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77998",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "F278L",
      "MUTATION_PDB": "F52L",
      "SEC_STR": "Beta",
      "RSA": "2.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": 1.73,
      "mu": -9.67,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77999",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "F278L",
      "MUTATION_PDB": "F52L",
      "SEC_STR": "Beta",
      "RSA": "2.5",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": 1.73,
      "mu": -9.67,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/77999",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T279A",
      "MUTATION_PDB": "T53A",
      "SEC_STR": "Beta",
      "RSA": "23.2",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.18,
      "mu": 2.01,
      "PhiF_H2O": 0.27,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/78000",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "T279A",
      "MUTATION_PDB": "T53A",
      "SEC_STR": "Beta",
      "RSA": "23.2",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -8.18,
      "mu": 2.01,
      "PhiF_H2O": 0.27,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/78000",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V280A",
      "MUTATION_PDB": "V54A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.94,
      "mu": 2.8,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/78001",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "Protein G",
      "SOURCE": "Streptococcus sp. GX7805",
      "LENGTH": 56.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_UNIPROT": "V280A",
      "MUTATION_PDB": "V54A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 22.0,
      "pH": 6.0,
      "BUFFER_NAME": "Sodium Phosphate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "GuHCl",
      "mf": -7.94,
      "mu": 2.8,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "McCallister, E.L., Alm, E., Baker, D.",
      "REFERENCE_KIN": "Critical role of beta-hairpin formation in protein G folding. Nat. Struct. Biol. 7, 669\u2013673. https://doi.org/10.1038/78001",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10932252",
      "STATE": "2",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-04T01:00:00"
   },
   {
      "PROTEIN": "C-terminal \u03b2-hairpin of protein GB",
      "SOURCE": "Streptococcus sp. group G",
      "LENGTH": 16.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_PDB": "WT",
      "T": 21.0,
      "pH": 7.0,
      "BUFFER_NAME": "KPi",
      "BUFFER_CONC": "0.02",
      "MEASURE_KIN": "T-jump",
      "METHOD_KIN": "thermal denaturation",
      "ln(kf)_H2O": 12.02,
      "ln(ku)_H2O": 12.02,
      "AUTHOR_KIN": "Mu\u00f1oz V, Thompson PA, Hofrichter J, Eaton WA",
      "REFERENCE_KIN": "Folding dynamics and mechanism of beta-hairpin formation. Nature. 1997  390(6656):196-9. https://doi.org/10.1038/36626",
      "YEAR_KIN": 1997.0,
      "PMID_KIN": "9367160",
      "STATE": "Yes",
      "REVIEW_DATE": "2023-06-09T01:00:00"
   },
   {
      "PROTEIN": "C-terminal \u03b2-hairpin of protein GB",
      "SOURCE": "Streptococcus sp. group G",
      "LENGTH": 16.0,
      "UniProt": "P06654",
      "PDB_wild": "1pgb",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF01378"
      ],
      "CATH": [
         "1pgbA00 (3.10.20.10)"
      ],
      "MUTATION_PDB": "WT",
      "T": 21.0,
      "pH": 7.0,
      "BUFFER_NAME": "KPi",
      "BUFFER_CONC": "0.02",
      "MEASURE_KIN": "T-jump",
      "METHOD_KIN": "thermal denaturation",
      "ln(kf)_H2O": 12.02,
      "ln(ku)_H2O": 12.02,
      "AUTHOR_KIN": "Mu\u00f1oz V, Thompson PA, Hofrichter J, Eaton WA",
      "REFERENCE_KIN": "Folding dynamics and mechanism of beta-hairpin formation. Nature. 1997  390(6656):196-9. https://doi.org/10.1038/36626",
      "YEAR_KIN": 1997.0,
      "PMID_KIN": "9367160",
      "STATE": "Yes",
      "REVIEW_DATE": "2023-06-09T01:00:00"
   }
]