[
   {
      "PROTEIN": "SH3 domain of the phosphatidylinositol 3-kinase regulatory subunit alpha",
      "SOURCE": "Bos taurus",
      "LENGTH": 84.0,
      "UniProt": "P23727",
      "PDB_wild": "1pnj",
      "MUTATED_CHAIN": "A",
      "CATH": [
         "1pnjA00 (2.30.30.40)"
      ],
      "MUTATION_PDB": "WT",
      "T": 20.0,
      "pH": 7.2,
      "BUFFER_NAME": "NaPi",
      "BUFFER_CONC": "0.02",
      "MEASURE_KIN": "manual mixing",
      "METHOD_KIN": "GdmCl",
      "ln(kf)_H2O": -1.04,
      "ln(ku)_H2O": -7.31,
      "dGKIN_H2O": 15.27,
      "AUTHOR_KIN": "Guijarro JI, Morton CJ, Plaxco KW, Campbell ID, Dobson CM",
      "REFERENCE_KIN": "Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy. J Mol Biol. 276(3):657-67. https://doi.org/10.1006/jmbi.1997.1553",
      "YEAR_KIN": 1998.0,
      "PMID_KIN": "9551103",
      "STATE": "Yes",
      "REVIEW_DATE": "2023-06-09T01:00:00"
   },
   {
      "PROTEIN": "SH3 domain of the phosphatidylinositol 3-kinase regulatory subunit alpha",
      "SOURCE": "Bos taurus",
      "LENGTH": 84.0,
      "UniProt": "P23727",
      "PDB_wild": "1pnj",
      "MUTATED_CHAIN": "A",
      "CATH": [
         "1pnjA00 (2.30.30.40)"
      ],
      "MUTATION_PDB": "WT",
      "T": 20.0,
      "pH": 7.2,
      "BUFFER_NAME": "NaPi",
      "BUFFER_CONC": "0.02",
      "MEASURE_KIN": "manual mixing",
      "METHOD_KIN": "GdmCl",
      "ln(kf)_H2O": -1.04,
      "ln(ku)_H2O": -7.31,
      "dGKIN_H2O": 15.27,
      "AUTHOR_KIN": "Guijarro JI, Morton CJ, Plaxco KW, Campbell ID, Dobson CM",
      "REFERENCE_KIN": "Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy. J Mol Biol. 276(3):657-67. https://doi.org/10.1006/jmbi.1997.1553",
      "YEAR_KIN": 1998.0,
      "PMID_KIN": "9551103",
      "STATE": "Yes",
      "REVIEW_DATE": "2023-06-09T01:00:00"
   }
]