[
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860A",
      "MUTATION_PDB": "I860A",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.37,
      "dln(kf)_H2O": -2.06,
      "ln(ku)_H2O": -8.2,
      "dln(ku)_H2O": 1.42,
      "PhiF_H2O": 0.6,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860A",
      "MUTATION_PDB": "I860A",
      "SEC_STR": "Beta",
      "RSA": "1.8",
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      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.37,
      "dln(kf)_H2O": -2.06,
      "ln(ku)_H2O": -8.2,
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      "PhiF_H2O": 0.6,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L863A",
      "MUTATION_PDB": "L863A",
      "SEC_STR": "Coil",
      "RSA": "7.3",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.65,
      "dln(kf)_H2O": -2.34,
      "ln(ku)_H2O": -4.84,
      "dln(ku)_H2O": 4.78,
      "PhiF_H2O": 0.33,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3529",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L863A",
      "MUTATION_PDB": "L863A",
      "SEC_STR": "Coil",
      "RSA": "7.3",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.65,
      "dln(kf)_H2O": -2.34,
      "ln(ku)_H2O": -4.84,
      "dln(ku)_H2O": 4.78,
      "PhiF_H2O": 0.33,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3529",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P865A",
      "MUTATION_PDB": "P865A",
      "SEC_STR": "Coil",
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      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.95,
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      "PhiF_H2O": 0.47,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P865A",
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      "SEC_STR": "Coil",
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      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
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      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T867S",
      "MUTATION_PDB": "T867S",
      "SEC_STR": "Coil",
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      "T": 25.0,
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "PhiF_H2O": 0.6,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3530",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
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      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T867S",
      "MUTATION_PDB": "T867S",
      "SEC_STR": "Coil",
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      "BUFFER_NAME": "Sodium Acetate",
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      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "PhiF_H2O": 0.6,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3530",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
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      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T867A",
      "MUTATION_PDB": "T867A",
      "SEC_STR": "Coil",
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "PhiF_H2O": 0.25,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
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      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
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      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T867A",
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      "SEC_STR": "Coil",
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      "MEASURE_KIN": "stopped-flow",
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      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
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      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y869F",
      "MUTATION_PDB": "Y869F",
      "SEC_STR": "Beta",
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3531",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y869F",
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      "SEC_STR": "Beta",
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "PhiF_H2O": 0.42,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3531",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
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      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "V871A",
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      "SEC_STR": "Beta",
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      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "PhiF_H2O": 0.54,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
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      "SEC_STR": "Beta",
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.87,
      "dln(kf)_H2O": -2.56,
      "ln(ku)_H2O": -7.44,
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      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L873A",
      "MUTATION_PDB": "L873A",
      "SEC_STR": "Beta",
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      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "ln(ku)_H2O": -5.93,
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      "PhiF_H2O": 0.29,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3532",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L873A",
      "MUTATION_PDB": "L873A",
      "SEC_STR": "Beta",
      "RSA": "0.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.22,
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      "ln(ku)_H2O": -5.93,
      "dln(ku)_H2O": 3.69,
      "PhiF_H2O": 0.29,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3532",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "S875A",
      "MUTATION_PDB": "S875A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.47,
      "dln(kf)_H2O": -0.22,
      "ln(ku)_H2O": -9.91,
      "dln(ku)_H2O": -0.29,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "S875A",
      "MUTATION_PDB": "S875A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.47,
      "dln(kf)_H2O": -0.22,
      "ln(ku)_H2O": -9.91,
      "dln(ku)_H2O": -0.29,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "G878A",
      "MUTATION_PDB": "G878A",
      "SEC_STR": "Coil",
      "RSA": "42.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.33,
      "dln(kf)_H2O": -0.36,
      "ln(ku)_H2O": -8.28,
      "dln(ku)_H2O": 1.34,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3533",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "G878A",
      "MUTATION_PDB": "G878A",
      "SEC_STR": "Coil",
      "RSA": "42.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.33,
      "dln(kf)_H2O": -0.36,
      "ln(ku)_H2O": -8.28,
      "dln(ku)_H2O": 1.34,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3533",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "S882A",
      "MUTATION_PDB": "S882A",
      "SEC_STR": "Coil",
      "RSA": "6.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.55,
      "dln(kf)_H2O": -0.14,
      "ln(ku)_H2O": -5.0,
      "dln(ku)_H2O": 4.62,
      "PhiF_H2O": 0.03,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "S882A",
      "MUTATION_PDB": "S882A",
      "SEC_STR": "Coil",
      "RSA": "6.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.55,
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      "ln(ku)_H2O": -5.0,
      "dln(ku)_H2O": 4.62,
      "PhiF_H2O": 0.03,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P884A",
      "MUTATION_PDB": "P884A",
      "SEC_STR": "Coil",
      "RSA": "51.5",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.6,
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      "ln(ku)_H2O": -9.53,
      "dln(ku)_H2O": 0.09,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3534",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P884A",
      "MUTATION_PDB": "P884A",
      "SEC_STR": "Coil",
      "RSA": "51.5",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
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      "ln(ku)_H2O": -9.53,
      "dln(ku)_H2O": 0.09,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3534",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "A885G",
      "MUTATION_PDB": "A885G",
      "SEC_STR": "Beta",
      "RSA": "26.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.3,
      "dln(kf)_H2O": -0.39,
      "ln(ku)_H2O": -8.17,
      "dln(ku)_H2O": 1.45,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "A885G",
      "MUTATION_PDB": "A885G",
      "SEC_STR": "Beta",
      "RSA": "26.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.3,
      "dln(kf)_H2O": -0.39,
      "ln(ku)_H2O": -8.17,
      "dln(ku)_H2O": 1.45,
      "PhiF_H2O": 0.21,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "E887A",
      "MUTATION_PDB": "E887A",
      "SEC_STR": "Beta",
      "RSA": "36.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.9,
      "dln(kf)_H2O": 0.21,
      "ln(ku)_H2O": -12.13,
      "dln(ku)_H2O": -2.51,
      "PhiF_H2O": 0.08,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3535",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "E887A",
      "MUTATION_PDB": "E887A",
      "SEC_STR": "Beta",
      "RSA": "36.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.9,
      "dln(kf)_H2O": 0.21,
      "ln(ku)_H2O": -12.13,
      "dln(ku)_H2O": -2.51,
      "PhiF_H2O": 0.08,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3535",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "E887G",
      "MUTATION_PDB": "E887G",
      "SEC_STR": "Beta",
      "RSA": "36.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.64,
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      "ln(ku)_H2O": -9.1,
      "dln(ku)_H2O": 0.52,
      "PhiF_H2O": 0.09,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "E887G",
      "MUTATION_PDB": "E887G",
      "SEC_STR": "Beta",
      "RSA": "36.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.64,
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      "ln(ku)_H2O": -9.1,
      "dln(ku)_H2O": 0.52,
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      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "F889A",
      "MUTATION_PDB": "F889A",
      "SEC_STR": "Beta",
      "RSA": "8.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.7,
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      "ln(ku)_H2O": -1.44,
      "dln(ku)_H2O": 8.18,
      "PhiF_H2O": 0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3536",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "F889A",
      "MUTATION_PDB": "F889A",
      "SEC_STR": "Beta",
      "RSA": "8.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.7,
      "dln(kf)_H2O": -0.99,
      "ln(ku)_H2O": -1.44,
      "dln(ku)_H2O": 8.18,
      "PhiF_H2O": 0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3536",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T891S",
      "MUTATION_PDB": "T891S",
      "SEC_STR": "Coil",
      "RSA": "17.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.16,
      "dln(kf)_H2O": -0.53,
      "ln(ku)_H2O": -6.91,
      "dln(ku)_H2O": 2.71,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T891S",
      "MUTATION_PDB": "T891S",
      "SEC_STR": "Coil",
      "RSA": "17.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.16,
      "dln(kf)_H2O": -0.53,
      "ln(ku)_H2O": -6.91,
      "dln(ku)_H2O": 2.71,
      "PhiF_H2O": 0.16,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T891A",
      "MUTATION_PDB": "T891A",
      "SEC_STR": "Coil",
      "RSA": "17.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.09,
      "dln(kf)_H2O": -0.6,
      "ln(ku)_H2O": -4.43,
      "dln(ku)_H2O": 5.19,
      "PhiF_H2O": 0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3537",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "T891A",
      "MUTATION_PDB": "T891A",
      "SEC_STR": "Coil",
      "RSA": "17.6",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.09,
      "dln(kf)_H2O": -0.6,
      "ln(ku)_H2O": -4.43,
      "dln(ku)_H2O": 5.19,
      "PhiF_H2O": 0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3537",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L893A",
      "MUTATION_PDB": "L893A",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.7,
      "dln(kf)_H2O": 0.01,
      "ln(ku)_H2O": -9.53,
      "dln(ku)_H2O": 0.09,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L893A",
      "MUTATION_PDB": "L893A",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.7,
      "dln(kf)_H2O": 0.01,
      "ln(ku)_H2O": -9.53,
      "dln(ku)_H2O": 0.09,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860A,V871A",
      "MUTATION_PDB": "I860A,V871A",
      "SEC_STR": "Beta,Beta",
      "RSA": "1.8,0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -2.3,
      "dln(kf)_H2O": -3.99,
      "ln(ku)_H2O": -5.74,
      "dln(ku)_H2O": 3.88,
      "PhiF_H2O": 0.51,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3538",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860A,V871A",
      "MUTATION_PDB": "I860A,V871A",
      "SEC_STR": "Beta,Beta",
      "RSA": "1.8,0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -2.3,
      "dln(kf)_H2O": -3.99,
      "ln(ku)_H2O": -5.74,
      "dln(ku)_H2O": 3.88,
      "PhiF_H2O": 0.51,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3538",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.69,
      "ln(ku)_H2O": -9.62,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3517",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "WT",
      "MUTATION_PDB": "WT",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.69,
      "ln(ku)_H2O": -9.62,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3517",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L803A",
      "MUTATION_PDB": "L803A",
      "SEC_STR": "Coil",
      "RSA": "37.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.55,
      "dln(kf)_H2O": -0.14,
      "ln(ku)_H2O": -6.2,
      "dln(ku)_H2O": 3.42,
      "PhiF_H2O": 0.04,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3517",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L803A",
      "MUTATION_PDB": "L803A",
      "SEC_STR": "Coil",
      "RSA": "37.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.55,
      "dln(kf)_H2O": -0.14,
      "ln(ku)_H2O": -6.2,
      "dln(ku)_H2O": 3.42,
      "PhiF_H2O": 0.04,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3517",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P806A",
      "MUTATION_PDB": "P806A",
      "SEC_STR": "Coil",
      "RSA": "5.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.53,
      "dln(kf)_H2O": -0.16,
      "ln(ku)_H2O": -5.16,
      "dln(ku)_H2O": 4.46,
      "PhiF_H2O": 0.04,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P806A",
      "MUTATION_PDB": "P806A",
      "SEC_STR": "Coil",
      "RSA": "5.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.53,
      "dln(kf)_H2O": -0.16,
      "ln(ku)_H2O": -5.16,
      "dln(ku)_H2O": 4.46,
      "PhiF_H2O": 0.04,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I809V",
      "MUTATION_PDB": "I809V",
      "SEC_STR": "Beta",
      "RSA": "7.7",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.46,
      "dln(kf)_H2O": -0.23,
      "ln(ku)_H2O": -9.55,
      "dln(ku)_H2O": 0.07,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3518",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I809V",
      "MUTATION_PDB": "I809V",
      "SEC_STR": "Beta",
      "RSA": "7.7",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.46,
      "dln(kf)_H2O": -0.23,
      "ln(ku)_H2O": -9.55,
      "dln(ku)_H2O": 0.07,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3518",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I809A",
      "MUTATION_PDB": "I809A",
      "SEC_STR": "Beta",
      "RSA": "7.7",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.2,
      "dln(kf)_H2O": -0.49,
      "ln(ku)_H2O": -5.28,
      "dln(ku)_H2O": 4.34,
      "PhiF_H2O": 0.1,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I809A",
      "MUTATION_PDB": "I809A",
      "SEC_STR": "Beta",
      "RSA": "7.7",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.2,
      "dln(kf)_H2O": -0.49,
      "ln(ku)_H2O": -5.28,
      "dln(ku)_H2O": 4.34,
      "PhiF_H2O": 0.1,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "V811A",
      "MUTATION_PDB": "V811A",
      "SEC_STR": "Beta",
      "RSA": "21.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.17,
      "dln(kf)_H2O": -0.52,
      "ln(ku)_H2O": -7.85,
      "dln(ku)_H2O": 1.77,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3519",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "V811A",
      "MUTATION_PDB": "V811A",
      "SEC_STR": "Beta",
      "RSA": "21.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.17,
      "dln(kf)_H2O": -0.52,
      "ln(ku)_H2O": -7.85,
      "dln(ku)_H2O": 1.77,
      "PhiF_H2O": 0.23,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3519",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "A819G",
      "MUTATION_PDB": "A819G",
      "SEC_STR": "Beta",
      "RSA": "2.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.02,
      "dln(kf)_H2O": -0.67,
      "ln(ku)_H2O": -5.56,
      "dln(ku)_H2O": 4.06,
      "PhiF_H2O": 0.14,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "A819G",
      "MUTATION_PDB": "A819G",
      "SEC_STR": "Beta",
      "RSA": "2.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.02,
      "dln(kf)_H2O": -0.67,
      "ln(ku)_H2O": -5.56,
      "dln(ku)_H2O": 4.06,
      "PhiF_H2O": 0.14,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I821V",
      "MUTATION_PDB": "I821V",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.07,
      "dln(kf)_H2O": -0.62,
      "ln(ku)_H2O": -9.86,
      "dln(ku)_H2O": -0.24,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3520",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I821V",
      "MUTATION_PDB": "I821V",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.07,
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      "ln(ku)_H2O": -9.86,
      "dln(ku)_H2O": -0.24,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3520",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I821A",
      "MUTATION_PDB": "I821A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.71,
      "dln(kf)_H2O": -2.4,
      "ln(ku)_H2O": -5.82,
      "dln(ku)_H2O": 3.8,
      "PhiF_H2O": 0.39,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I821A",
      "MUTATION_PDB": "I821A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.71,
      "dln(kf)_H2O": -2.4,
      "ln(ku)_H2O": -5.82,
      "dln(ku)_H2O": 3.8,
      "PhiF_H2O": 0.39,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P826A",
      "MUTATION_PDB": "P826A",
      "SEC_STR": "Coil",
      "RSA": "2.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 2.13,
      "dln(kf)_H2O": 0.44,
      "ln(ku)_H2O": -6.26,
      "dln(ku)_H2O": 3.36,
      "PhiF_H2O": -0.1,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3521",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P826A",
      "MUTATION_PDB": "P826A",
      "SEC_STR": "Coil",
      "RSA": "2.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 2.13,
      "dln(kf)_H2O": 0.44,
      "ln(ku)_H2O": -6.26,
      "dln(ku)_H2O": 3.36,
      "PhiF_H2O": -0.1,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3521",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I830V",
      "MUTATION_PDB": "I830V",
      "SEC_STR": "Coil",
      "RSA": "2.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.54,
      "dln(kf)_H2O": -0.15,
      "ln(ku)_H2O": -9.23,
      "dln(ku)_H2O": 0.39,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I830V",
      "MUTATION_PDB": "I830V",
      "SEC_STR": "Coil",
      "RSA": "2.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.54,
      "dln(kf)_H2O": -0.15,
      "ln(ku)_H2O": -9.23,
      "dln(ku)_H2O": 0.39,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I830A",
      "MUTATION_PDB": "I830A",
      "SEC_STR": "Coil",
      "RSA": "2.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.39,
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      "ln(ku)_H2O": -7.59,
      "dln(ku)_H2O": 2.03,
      "PhiF_H2O": 0.13,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3522",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I830A",
      "MUTATION_PDB": "I830A",
      "SEC_STR": "Coil",
      "RSA": "2.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.39,
      "dln(kf)_H2O": -0.3,
      "ln(ku)_H2O": -7.59,
      "dln(ku)_H2O": 2.03,
      "PhiF_H2O": 0.13,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3522",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I833V",
      "MUTATION_PDB": "I833V",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.31,
      "dln(kf)_H2O": -0.38,
      "ln(ku)_H2O": -9.16,
      "dln(ku)_H2O": 0.46,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I833V",
      "MUTATION_PDB": "I833V",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.31,
      "dln(kf)_H2O": -0.38,
      "ln(ku)_H2O": -9.16,
      "dln(ku)_H2O": 0.46,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I833A",
      "MUTATION_PDB": "I833A",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.66,
      "dln(kf)_H2O": -1.03,
      "ln(ku)_H2O": -5.12,
      "dln(ku)_H2O": 4.5,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3523",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I833A",
      "MUTATION_PDB": "I833A",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.66,
      "dln(kf)_H2O": -1.03,
      "ln(ku)_H2O": -5.12,
      "dln(ku)_H2O": 4.5,
      "PhiF_H2O": 0.19,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3523",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L835A",
      "MUTATION_PDB": "L835A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.82,
      "dln(kf)_H2O": -2.51,
      "ln(ku)_H2O": -4.89,
      "dln(ku)_H2O": 4.73,
      "PhiF_H2O": 0.35,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L835A",
      "MUTATION_PDB": "L835A",
      "SEC_STR": "Beta",
      "RSA": "0.0",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.82,
      "dln(kf)_H2O": -2.51,
      "ln(ku)_H2O": -4.89,
      "dln(ku)_H2O": 4.73,
      "PhiF_H2O": 0.35,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y837F",
      "MUTATION_PDB": "Y837F",
      "SEC_STR": "Beta",
      "RSA": "17.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.74,
      "dln(kf)_H2O": 0.05,
      "ln(ku)_H2O": -8.83,
      "dln(ku)_H2O": 0.79,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3524",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y837F",
      "MUTATION_PDB": "Y837F",
      "SEC_STR": "Beta",
      "RSA": "17.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.74,
      "dln(kf)_H2O": 0.05,
      "ln(ku)_H2O": -8.83,
      "dln(ku)_H2O": 0.79,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3524",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y837A",
      "MUTATION_PDB": "Y837A",
      "SEC_STR": "Beta",
      "RSA": "17.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -2.04,
      "dln(kf)_H2O": -3.73,
      "ln(ku)_H2O": -6.23,
      "dln(ku)_H2O": 3.39,
      "PhiF_H2O": 0.53,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y837A",
      "MUTATION_PDB": "Y837A",
      "SEC_STR": "Beta",
      "RSA": "17.1",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -2.04,
      "dln(kf)_H2O": -3.73,
      "ln(ku)_H2O": -6.23,
      "dln(ku)_H2O": 3.39,
      "PhiF_H2O": 0.53,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P843A",
      "MUTATION_PDB": "P843A",
      "SEC_STR": "Coil",
      "RSA": "82.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.81,
      "dln(kf)_H2O": -0.88,
      "ln(ku)_H2O": -9.73,
      "dln(ku)_H2O": -0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3525",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "P843A",
      "MUTATION_PDB": "P843A",
      "SEC_STR": "Coil",
      "RSA": "82.4",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.81,
      "dln(kf)_H2O": -0.88,
      "ln(ku)_H2O": -9.73,
      "dln(ku)_H2O": -0.11,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3525",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "G844A",
      "MUTATION_PDB": "G844A",
      "SEC_STR": "Coil",
      "RSA": "90.5",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.6,
      "dln(kf)_H2O": -0.09,
      "ln(ku)_H2O": -9.12,
      "dln(ku)_H2O": 0.5,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "G844A",
      "MUTATION_PDB": "G844A",
      "SEC_STR": "Coil",
      "RSA": "90.5",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 1.6,
      "dln(kf)_H2O": -0.09,
      "ln(ku)_H2O": -9.12,
      "dln(ku)_H2O": 0.5,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I849A",
      "MUTATION_PDB": "I849A",
      "SEC_STR": "Beta",
      "RSA": "21.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.76,
      "dln(kf)_H2O": -2.45,
      "ln(ku)_H2O": -8.38,
      "dln(ku)_H2O": 1.24,
      "PhiF_H2O": 0.67,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3526",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I849A",
      "MUTATION_PDB": "I849A",
      "SEC_STR": "Beta",
      "RSA": "21.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.76,
      "dln(kf)_H2O": -2.45,
      "ln(ku)_H2O": -8.38,
      "dln(ku)_H2O": 1.24,
      "PhiF_H2O": 0.67,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3526",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L851A",
      "MUTATION_PDB": "L851A",
      "SEC_STR": "Beta",
      "RSA": "4.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.43,
      "dln(kf)_H2O": -2.12,
      "ln(ku)_H2O": -6.69,
      "dln(ku)_H2O": 2.93,
      "PhiF_H2O": 0.42,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "L851A",
      "MUTATION_PDB": "L851A",
      "SEC_STR": "Beta",
      "RSA": "4.9",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.43,
      "dln(kf)_H2O": -2.12,
      "ln(ku)_H2O": -6.69,
      "dln(ku)_H2O": 2.93,
      "PhiF_H2O": 0.42,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y858A",
      "MUTATION_PDB": "Y858A",
      "SEC_STR": "Beta",
      "RSA": "30.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.82,
      "dln(kf)_H2O": -0.87,
      "ln(ku)_H2O": -8.16,
      "dln(ku)_H2O": 1.46,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3527",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y858A",
      "MUTATION_PDB": "Y858A",
      "SEC_STR": "Beta",
      "RSA": "30.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.82,
      "dln(kf)_H2O": -0.87,
      "ln(ku)_H2O": -8.16,
      "dln(ku)_H2O": 1.46,
      "PhiF_H2O": 0.38,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3527",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y858G",
      "MUTATION_PDB": "Y858G",
      "SEC_STR": "Beta",
      "RSA": "30.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.03,
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      "ln(ku)_H2O": -4.35,
      "dln(ku)_H2O": 5.27,
      "PhiF_H2O": 0.25,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "Y858G",
      "MUTATION_PDB": "Y858G",
      "SEC_STR": "Beta",
      "RSA": "30.2",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": -0.03,
      "dln(kf)_H2O": -1.72,
      "ln(ku)_H2O": -4.35,
      "dln(ku)_H2O": 5.27,
      "PhiF_H2O": 0.25,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78.",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860V",
      "MUTATION_PDB": "I860V",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.8,
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      "ln(ku)_H2O": -9.11,
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      "PhiF_H2O": 0.64,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3528",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   },
   {
      "PROTEIN": "Tenascin, TNfn3 domain",
      "SOURCE": "Homo sapiens",
      "LENGTH": 92.0,
      "UniProt": "P24821",
      "PDB_wild": "1ten",
      "MUTATED_CHAIN": "A",
      "PFAM": [
         "PF00041"
      ],
      "CATH": [
         "1tenA00 (2.60.40.10)"
      ],
      "MUTATION_UNIPROT": "I860V",
      "MUTATION_PDB": "I860V",
      "SEC_STR": "Beta",
      "RSA": "1.8",
      "T": 25.0,
      "pH": 5.0,
      "BUFFER_NAME": "Sodium Acetate",
      "BUFFER_CONC": "0.05",
      "MEASURE_KIN": "stopped-flow",
      "METHOD_KIN": "alkaline unfolding (pH 12.4)",
      "ln(kf)_H2O": 0.8,
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      "ln(ku)_H2O": -9.11,
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      "PhiF_H2O": 0.64,
      "AUTHOR_KIN": "Hamill SJ, Steward A, Clarke J",
      "REFERENCE_KIN": "The folding of an immunoglobulin-like Greek key protein is defined by a common-core nucleus and regions constrained by topology. J Mol Biol. 297(1):165-78. https://doi.org/10.1006/jmbi.2000.3528",
      "YEAR_KIN": 2000.0,
      "PMID_KIN": "10704314",
      "STATE": "Yes",
      "REVERSIBILITY": "Yes",
      "REVIEW_DATE": "2023-06-11T01:00:00"
   }
]